The story of a perpetually engaged man and woman having an open love affair with a pair of imaginary fantasy figures closes out In Tandem’s 10th anniversary season. Jeremy Desmon’s The Girl in the Frame plays at the 10th Street Theatre through June 15. Simon Jon Provan plays a guy named Alex who never seems to get the time he needs with his fiancée Laney (Alison Mary Forbes). When she is called away on business, he is left to fantasize about a girl in a stock photo from a picture frame (Courtney Jones) who comes to life to entertain him. When Laney returns to the apartment, she is soon caught up in her own fantasy with a model from a fireman calendar (Travis A. Knight).

Ladies, please have mercy on your poor husbands and resist the urge to drag them to Menopause: The Musical. The popular touring production begins its month-long run at the Marcus Center tonight with a 7:30 p.m. performance, but no man can withstand that many concentrated jokes about hot flashes, mood swings . . .

Sunset Playhouse tackles a tough challenge with its latest production, The Boys Next Door. Written in 1985, the play attempts to raise awareness of issues faced by the cognitively disabled. Often, this type of “message” play is long on exposition and short on entertainment. The Sunset production, however, manages to balance both elements quite well. Credit goes to director Mark Salentine for keeping the show on task throughout its two-and-a-half-hour running time.

The Sunset Playhouse’s latest production mines humor from one of the most unlikely, sensitive sources: people with developmental disabilities. Tom Griffin’s comic drama The Boys Next Door deftly walks the line people complexity and accessibility by treating its characters as three-dimensional human beings instead of resorting . . .

Tonight at 7:30 p.m. at the Off Broadway Theatre, Next Act Theatre continues its production of Charles Ludlam’s Mystery of Irma Vep: A Penny Dreadful, a popular, idiosyncratic masterpiece starring John McGivern and Christopher Tarjan, and directed by the company’s artistic director, David Cecsarini. The play . . .

A beautiful but deceptive villainess—murderess?—named Lydia Gwilt is at the center of the Milwaukee Repertory Theater’s production of Armadale, an adaptation of the 19th-century Wilkie Collins novel of the same name. The Rep performs this complicated, sensational story of fraud, love affairs and confused identities . . .

Robb Smith plays an American college professor working overseas in Beirut who is captured by terrorists. Forced to take in the world around him through sound alone, the professor spends much of his time trying analyzing the social complexity of his situation. Smith has a firm grasp on the character’s intellectual side, rendering an intelligent performance that is solidly rooted in emotional reality.

Spiral Theater opens their two-weekend production of Lee Blessing’s tense drama on American/Middle Eastern relations, Two Rooms, tonight with an 8 p.m. performance at Bucketworks. The play depicts the symbolic connection between a college professor, kidnapped and blindfolded somewhere in Beirut, and . . .

In 1952, scriptwriter George Axelrod scored a major success with The Seven Year Itch, a Broadway comedy about a married man whose fantasy life gets a little out of control when he meets a beautiful young woman. Decades later, Jeremy Desmon updated the story in a compelling exploration of extramarital fantasy with The Girl in the Frame.

The third annual Play in a Day hit the Tenth Street Theatre this past weekend. A joint project between DIY theater groups Insurgent Theatre and Alamo Basement, Play in a Day comes from the rather absurd notion of making an entire play in 24 hours complete with sets and costuming. The hope here is to blur the line between performance and process. To a certain extent the final show is merely a rehearsal for a more balanced show that will never be completed. Ideally, things feel rough and incomplete.